By Syed Raza Hassan

KARACHI, Pakistan (Reuters) - Gunmen on motorcycles killed at least four people at a religious gathering of Shi'ite Muslims in Karachi, Pakistan's largest city, on Saturday, police said, in the latest attack claimed by the Sunni militant group Lashkar-e-Jhangvi's Al Alami faction.

The shooting took place in the North Nazimabad neighborhood of the sprawling metropolis of more than 18 million people, where sectarian, ethnic and political violence is common.

Lashkar-e-Jhangvi's Al Alami faction, which targets Shi'ites and Pakistan's security forces, killed more than 60 police cadets in the southwestern city of Quetta on Monday in an attack in conjunction with Islamic State.

But it said it carried out this attack on its own.

"Lashkar-e-Jhangvi Al Alami accepts responsibility for those killed in this attack, and we announce that there is no room for the enemies of the companions of the Prophet Muhammad in Pakistan," said Ali bin Sufyan, the group's spokesperson, in a statement.

Provincial police chief Allah Dino Khwaja told reporters men on two motorcycles fired on the gathering.

Four people were killed and three others wounded, Nasir Aftab, a senior police officer, said.

Violent crime has dropped significantly in Karachi since the launch of a paramilitary operation in the city three years ago, but targeted attacks still occur frequently.

Shi'ite Muslims make up about 20 percent of Pakistan's 190 million people, and sectarian attacks against them - including bombings and targeted attacks - have become increasingly common in recent years.

Since 2002, more than 2,500 Shi'ite Muslims have been killed in such attacks, according to data gathered by the South Asia Terrorism Portal. At least 23 people have been killed in such attacks this year, it said.

(Additional reporting by Saud Mehsud in DERA ISMAIL KHAN; Writing by Asad Hashim; Editing by Alison Williams and Stephen Powell)