By Anshuman Daga and Sumeet Chatterjee

SINGAPORE/HONG KONG (Reuters) - Standard Chartered <STAN.L> is set to cut about a tenth of its global corporate and institutional banking headcount, sources with direct knowledge of the matter said on Monday, as the bank steps up an aggressive drive to cut costs.

Chief Executive Bill Winters this month branded the bank's income and profit unacceptable, as below-forecast third-quarter results underlined the challenges facing his overhaul.

The job cuts will be rolled out beginning this week across all the major business centers starting with Singapore and Hong Kong, one of the sources told Reuters. All the sources declined to be named because they were not authorized to speak to the media.

"We are making our corporate and institutional banking division more efficient," a Standard Chartered spokesman said, without revealing how many jobs are to be axed.

"Removing duplication in roles and managing our costs to protect planned investments in technology and people means that a small number of existing roles will be impacted."

Former JPMorgan <JPM.N> investment banker Winters has already moved to close the stock trading business and raise $5.1 billion in capital.

These efforts have paid off for Standard Chartered's bottom line, and its third quarter result marked a second consecutive quarter of profit after it swung to an annual loss for 2015, when it was hit by the costs of revamping its management team.

Winter also said in November last year the bank would cut 15,000 jobs. It was not immediately clear whether the cuts in corporate and institutional banking formed part of that.

The latest headcount cut marks the first major move by former senior HSBC <HSBA.L> banker Simon Cooper who joined in April as chief executive of corporate and institutional banking.

Cooper has been working to overhaul and streamline the structure of the corporate and institutional banking division, the largest unit of the bank accounting for more than 46 percent of its operating income in the six months ended June.

It was not immediately clear how many of the global total of 84,477 employees at the British bank at the end of June were in that division.

Returns from the bank's corporate and institutional banking, which includes corporate finance and transaction banking, were hurt by loan impairments and high expenses, Standard Chartered said in last year's annual report.

In the quarter ended September, Standard Chartered corporate and institutional banking income dropped 7.5 percent from the year-ago period to $1.6 billion, pulling the bank's total operating income down nearly 6 percent.

Separately, the bank said Ajay Kanwal would step down from his role as regional CEO for ASEAN and South Asia with immediate effect. Anna Marrs, CEO of commercial and private banking, will add the role to her existing position.

In a statement issued by Standard Chartered, Kanwal, who had been with the bank since 1992, said he had resigned after he failed to disclose his past personal investments outside the bank.

"Though I do not own these investments any more, as a senior leader my actions should be beyond reproach. Hence with regret I have decided to tender my resignation," he said.

Kanwal, whose senior roles at Standard Chartered <2888.HK> included regional CEO for North East Asia and CEO for Taiwan, could not be immediately reached for comment by Reuters.

(Reporting by Anshuman Daga and Sumeet Chatterjee; Additional reporting by Lawrence White in London; Editing by Muralikumar Anantharaman/Ruth Pitchford)