The White House on Tuesday released an anti-rape video highlighting the importance of sexual consent.

The video, titled “The One Thing,” includes cameos from celebrities like Zoe Saldana, Josh Hutcherson, Matt McGorry and John Cho.

It was published on YouTube and is part of President Barack Obama’s “It’s On Us” campaign, which was first launched in September 2014.

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“There’s one thing you can never have sex without,” says Saldana.

Cho finishes her thought: “It’s consent.”

The powerful message comes at a time when millions of students are returning to school. Campus rape has been an ongoing battle in the U.S., and the White House video is one of many public campaigns to eradiate sexual violence from colleges and universities. 

The “It's On Us” has now been launched in a total of 300 colleges, which have hosted 650 events addressing sexual assault on campus, Mic.com reported. More than 220,000 people have pledged to take on the issue at their school.

The campaign's videos have collected more than 10 million views.

Watch the video below.