Didi Gregorius will take over for Derek Jeter as the Yankees' shortstop.Getty Images

The 2015 Major League Baseball regular season begins on Sunday, April 5 when the Cardinals play at the Cubs (8 p.m., ESPN). St. Louis – Chicago is the only MLB game that day.

The rest of the baseball world will kick things off on Monday, April 6, highlighted by Blue Jays at Yankees at 1:05 p.m. and Red Sox at Phillies at 3:05 p.m.

The Nationals will host the Mets at 4:05 p.m. that Monday.