(Reuters) - New York Giants wide receiver Odell Beckham Jr. will undergo season-ending surgery this week to repair the left ankle he injured during the team's loss to the Los Angeles Chargers on Sunday, coach Ben McAdoo said.
After a Chargers defender landed on his ankle following a short passing route in the fourth quarter of the game, Beckham covered his face with one hand and held his leg with the other as he was taken off the field.
The 24-year-old had previously sprained his ankle during the preseason game against the Cleveland Browns in August.
"I spoke to Odell after the game. It's a sad situation. It's fair to say his season is over," McAdoo said in quotes posted on the team's Twitter feed.
Beckham has reached the Pro Bowl in each of his first three seasons in the NFL, establishing himself as one of the league's most dangerous receivers.
The injury is a heartbreaking one for the American, who was looking to use a huge season to negotiate a contract that would make him one of the highest paid players in the league.
It is also a significant setback for the Giants, who are 0-5 this season after Sunday's 27-22 loss to the previously winless Chargers.
(Reporting by Rory Carroll; Editing by Christian Radnedge)