Angelina Jolie reportedly walked out on Brad Pitt following a furious argument last weekend, reports.

The couple — who raise six children together — allegedly had a huge row following their twins Knox and Vivienne’s first birthday bash at their rented Los Angeles home Sunday.

According to sources, the 34-year-old beauty booked into a room at a luxury Beverly Hills hotel after collapsing on the floor in a flood of tears at the party.

A source told Britain’s Grazia magazine: “Minutes after the argument, she got up, threw together a bag of clothes and ran to her car. She checked straight into a suite at the Raffles L’Ermitage hotel.”

The actress has reportedly remained at the hotel — where her late mother Marcheline Bertrand stayed until her death in 2007 — and is refusing to speak to Pitt.

The source explained: “Angelina is refusing to take Brad’s calls — the only way he knew she was OK was because the nannies had seen her ... She’s always thrilled to see the kids, who have been visiting two at a time.”

Friends of the actress say Jolie is still mourning her mother, who died of ovarian cancer at age 56.

One said: “Angelina stays in the room for hours on end. It’s as if she’s trying to feel Marcheline’s spirit. She’s lighting candles and thinking about her mother.”

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