State health officials released new regulations on how it would deal with any further spread of the deadly Legionnaires' disease that has already killed 12 New Yorkers.

The new guidelines come days after the de Blasio administration bumped up the reported number of New Yorkers with Legionnaires' disease to 124.

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Gov. Andrew Cuomo's office said it consulted with New York City officials to draft the rules, which include a public free hotline and detailed requirements for cooling tower maintenance.

"I want to reassure all New Yorkers: We are addressing the problem at its source and protecting the public health, statewide," the governor said in a statement Monday.

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The outlined rules double down on a series of reforms passed by the City Council last week. All cooling towers will have to be registered with both the state and city health departments, and tests must be conducted every four months.

On Saturday, the de Blasio administration said the number of patients being treated for the severe form of bacterial pneumonia grew by three. The number of deaths — all adults found to be ill with underlying issues — remains at 12.

Cuomo and de Blasio previously held conflicting press conferences on the outbreak, fueling persistent rumors of conflict between City Hall and the governor's office.

New Yorkers can call 1-888-769-7243 for questions about the statewide regulations.