You already know about the devastating injuries. No more Odell Beckham, Dalvin Cook or Marcus Mariota (at least for a little while). But what about minor injuries to players many fantasy football owners are hoping play this week?
Here's the latest on a few key names:
Travis Kelce, TE, Chiefs
After leaving last Sunday's game, returning, and then leaving again with a head injury, Kansas City's rough-running tight end Kelce has not practiced this week due to concussion-like symptoms. His ability to play in Week 6 will depend on his standing in the NFL's concussion protocol.
Stefon Diggs, WR, Vikings
Two things that are hurting Diggs' fantasy value. 1. The Vikings can't figure out what to do at quarterback with Case Keenum and Sam Bradford. 2. He hurt his groin and left Week 5's game. He is questionable this week but a gamble to start either way. Avoid if you can.
Rob Gronkowski, TE, Tom Brady, QB, Patriots
The two biggest names on the Patriots offense are nursing minor injuries. Gronk missed last week's game against the Bucs due to an injured thigh. Brady has shoulder pain. Both are back in practice and likely to play in Week 6.
Sterling Shepard, WR, Giants
The only of the four injured Giants wideouts expected to possibly return this season, it won't be in Week 6 as he works his way back from an ankle injury.
Bilal Powell, RB, Jets
Out of practice again Wednesday, it's not looking good for Powell's playing status. With Matt Forte also injured, Elijah McGuire could be the man called on as starter with Travaris Cadet as his backup. Both are risks but could be targeted with desperation in fantasy leagues.