A Bronx man died Wednesday night after police used a Taser on him as he threatened them with a glass bottle, investigators said.

Three officers and a sergeant responded to a 911 call about an emotionally disturbed man threatening a neighbor with a knife at a 1840 Mayflower Ave. apartment in Pelham Bay.

When the officers confronted the man, whose identity hasn't been disclosed by investigators, he threatened them with an intact bottle.

The sergeant discharged a Taser twice on the 49-year-old man, and he was then taken into custody. He went into cardiac arrest, and CPR was administered by police personnel, the NYPD said. The man was taken to Einstein Hospital, where he died around 7:22 p.m.

The department’s Force Investigation Division is looking into the incident, which comes just two weeks after police fatally shot 66-year-old Bronx resident Deborah Danner

A neighbor made an emergency call that Danner, who suffered from schizophrenia, was acting irrationally, reports said. After Sgt. Hugh Barry discovered Danner holding scissors, he persuaded her to put them down. She then reportedly charged at him with a baseball bat, and Barry shot Danner twice. 

The department came under fire for the officer not using a Taser to subdue Danner.